您现在的位置:食品科学网>新闻资讯>正文

Wolfberry extracts inhibit Aβ1-42 aggregation and

阅读:12561
2020-03-31 10:00:32; 来源:
责任编辑:食品科学
0

Wolfberry extracts inhibit Aβ1-42 aggregation and rescue memory loss of AD drosophila

This study is to investigate the potential of wolfberry water extracts for the treatment of Alzheimer’s disease (AD) and the relationship between their anti-AD property and the geographic locations in China. Total extracts of all wolfberry samples showed the potent to decrease self-induced Aβ1-42 aggregation and Cu2+-induced Aβ1-42 aggregation and the antioxidant capacity as well as the bioactivity for binding biometal. A transgenic drosophila model assay revealed that TE of S1 and S6 (S1-TE and S6-TE) at 100 g/mL demonstrated the potent rescue effect on memory loss compared to the positive control memantine at 20 g/mL. Further study also revealed the polysaccharide extracts could contribute to their anti-AD property, and the anti-AD activity conspicuously depends on growing environment. Wolfberry samples S1 and S6 showed much more potent anti-AD property. Meanwhile this study demonstrated that the Chinese commonly consumed wolfberry in boiling water might have the beneficial function to prevent AD pathology.


Wolfberry extracts inhibit Aˇ1-42 aggregation and rescue memory loss of AD drosophila

相关阅读

  • 来源:新京报  |  2016-05-19
    阅读:386

    中粮1元“贱卖”君顶酒庄或因巨债流拍

    4月15日,北京产权交易中心挂出“中粮旗下中国食品拟1元底价拍卖中粮君顶酒庄55%股权”的消息,引起行业一片哗然。1元拍卖的背后实则附有昂贵的“条件”,中标者需承担君顶酒庄所欠中粮3.92亿元的债务,而其实际对外欠账总额高达5亿多元。

  • 来源:新京报  |  2016-05-19
    阅读:386

    央视记者随机买8份草莓 均检出可致癌农药残留

    京华时报讯(记者常鑫),前天,央视财经频道《是真的吗》节目播出一组有关草莓的报道,称该栏目组记者随机在北京购买的8份草莓均检测出含有百菌清和乙草胺两种农药。

  • 来源:新京报  |  2016-05-19
    阅读:386

    麦当劳奶昔退役 业内分析恐因销量下挫

    曾在麦当劳中国餐厅服役近24年的奶昔昨日正式谢幕。虽然麦当劳中国方面称此举属正常产品调整,不过在业内看来,销量的不断下滑或才是此次奶昔下架的真正原因。

微博

食品科学服务号

食品科学订阅号

食品书店

食品科学

定价:25.00¥
会员价:20.00¥

合作伙伴